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MK-677 is an orally administered growth hormone secretagogue. A secretagogue is a substance that promotes secretion. By this standard, MK-677 can be compared to peptides such as GHRP-6 or Ipamorelin. MK-677 was developed with the intention of combating conditions such as muscle atrophy, osteoporosis and obesity.MK-677 was shown to increase IGF-1 levels by between 39-89% in several studies.

Benefits have been shown to include:

  • improved sleep

  • anabolic to androgenic ratio of 25:1

  • boosts immune system

  • aid in weight loss by increasing fat loss

  • helps increase lean muscle mass

  • promotes nocturnal pulses of growth hormone

  • increases insulin-like growth factor-binding protein 3 (IGFBP-3)

  • beneficial for athletes and the elderly

  • increases muscle strength

  • reduces muscle-wasting

  • increases bone density

  • combats aging and has been shown to increase longevity in some studies

  • increases IGF-1, which is known to improve memory and learning

  • improves cognitive function

  • some studies have shown that it is beneficial in treating growth hormone deficiency

** For research purposes only, all of the above information is anecdotal and has not been evaluated by any regulatory body in North America **

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